CHM antibody

Catalog No. ABIN7266354

This anti-CHM antibody is a Rabbit Monoclonal antibody detecting CHM in WB. Suitable for Human.

Quick Overview for CHM antibody (ABIN7266354)

Target: CHM (Choroideremia (Rab Escort Protein 1) (CHM))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CHM antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CHM Antibody

Purpose: CHM Rabbit mAb

Cross-Reactivity: Human

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human CHM.

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CHM

Target: CHM (Choroideremia (Rab Escort Protein 1) (CHM))

Alternative Name: CHM

Background: This gene encodes component A of the RAB geranylgeranyl transferase holoenzyme. In the dimeric holoenzyme, this subunit binds unprenylated Rab GTPases and then presents them to the catalytic Rab GGTase subunit for the geranylgeranyl transfer reaction. Rab GTPases need to be geranylgeranyled on either one or two cysteine residues in their C-terminus to localize to the correct intracellular membrane. Mutations in this gene are a cause of choroideremia, also known as tapetochoroidal dystrophy (TCD). This X-linked disease is characterized by progressive dystrophy of the choroid, retinal pigment epithelium and retina. Alternatively spliced transcript variants have been found for this gene.,CHM, DXS540, GGTA, HSD-32, REP-1, TCD, CHM, Rab escort protein 1,Signal Transduction,Neuroscience,CHM

Molecular Weight: 95kDa

Gene ID: 1121

UniProt: P24386

Pathways: Sensory Perception of Sound