CDK2 antibody (pTyr15)

Catalog No. ABIN7266586

This Rabbit Monoclonal antibody specifically detects CDK2 in WB. It exhibits reactivity toward Human.

Quick Overview for CDK2 antibody (pTyr15) (ABIN7266586)

Target: CDK2 (Cyclin-Dependent Kinase 2 (CDK2))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CDK2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CDK2 Antibody

Binding Specificity: pTyr15

Purpose: Phospho-CDK2-Y15 Rabbit mAb

Cross-Reactivity: Human, Mouse

Characteristics: Phosphorylated Antibodies

Purification: Affinity purification

Immunogen: A phospho specific peptide corresponding to residues surrounding Y15 of human CDK2

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CDK2

Target: CDK2 (Cyclin-Dependent Kinase 2 (CDK2))

Alternative Name: CDK2

Background: This gene encodes a member of a family of serine/threonine protein kinases that participate in cell cycle regulation. The encoded protein is the catalytic subunit of the cyclin-dependent protein kinase complex, which regulates progression through the cell cycle. Activity of this protein is especially critical during the G1 to S phase transition. This protein associates with and regulated by other subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A), and p27Kip1 (CDKN1B). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014],CDKN2, p33(CDK2),Cancer,Cell Biology & Developmental Biology,Cell Cycle,Cell Cycle_Centrosome,DNA Damage & Repair,Epigenetics & Nuclear Signaling,G1/S Checkpoint,Kinase,Kinase_Serine/threonine kinases,Protein phosphorylation,Signal Transduction,CDK2

Molecular Weight: 34kDa

Gene ID: 1017

UniProt: P24941

Pathways: PI3K-Akt Signaling, Cell Division Cycle, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA