CYBA antibody (AA 126-195)

Catalog No. ABIN7266628

This Rabbit Polyclonal antibody specifically detects CYBA in IHC. It exhibits reactivity toward Human.

Quick Overview for CYBA antibody (AA 126-195) (ABIN7266628)

Target: CYBA (Cytochrome B-245, alpha Polypeptide (CYBA))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CYBA antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-CYBA Antibody

Binding Specificity: AA 126-195

Purpose: CYBA Rabbit pAb

Sequence: VRGEQWTPIE PKPRERPQIG GTIKQPPSNP PPRPPAEARK KPSEEEAAVA AGGPPGGPQV NPIPVTDEVV

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 126-195 of human CYBA (NP_000092.2).

Isotype: IgG

Application Details

Application Notes: IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CYBA

Target: CYBA (Cytochrome B-245, alpha Polypeptide (CYBA))

Alternative Name: CYBA

Background: Cytochrome b is comprised of a light chain (alpha) and a heavy chain (beta). This gene encodes the light, alpha subunit which has been proposed as a primary component of the microbicidal oxidase system of phagocytes. Mutations in this gene are associated with autosomal recessive chronic granulomatous disease (CGD), that is characterized by the failure of activated phagocytes to generate superoxide, which is important for the microbicidal activity of these cells.,CYBA,p22-PHOX,Cancer,Cell Biology & Developmental Biology,Endocrine & Metabolism,Mitochondrial metabolism,Cytochromes,Immunology & Inflammation,CYBA

Molecular Weight: 21kDa

Gene ID: 1535

UniProt: P13498

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones, Carbohydrate Homeostasis