Dihydrofolate Reductase antibody

Catalog No. ABIN7266764

The Rabbit Monoclonal anti-Dihydrofolate Reductase antibody is suitable to detect Dihydrofolate Reductase in samples from Human. It has been validated for WB.

Quick Overview for Dihydrofolate Reductase antibody (ABIN7266764)

Target: Dihydrofolate Reductase (DHFR)

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Dihydrofolate Reductase antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Dihydrofolate Reductase Antibody

Purpose: DHFR Rabbit mAb

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human DHFR

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Dihydrofolate Reductase

Target: Dihydrofolate Reductase (DHFR)

Alternative Name: DHFR

Background: Dihydrofolate reductase converts dihydrofolate into tetrahydrofolate, a methyl group shuttle required for the de novo synthesis of purines, thymidylic acid, and certain amino acids. While the functional dihydrofolate reductase gene has been mapped to chromosome 5, multiple intronless processed pseudogenes or dihydrofolate reductase-like genes have been identified on separate chromosomes. Dihydrofolate reductase deficiency has been linked to megaloblastic anemia. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2014],DHFRP1, DYR,Amino acid metabolism,Cancer,Cell Biology & Developmental Biology,Endocrine & Metabolism,Nucleotide metabolism,Signal Transduction,DHFR

Molecular Weight: 21kDa

Gene ID: 1719

UniProt: P00374

Pathways: Mitotic G1-G1/S Phases