DYNLRB1 antibody (AA 1-63)

Catalog No. ABIN7266866

Product Details anti-DYNLRB1 Antibody

Target: DYNLRB1 (Dynein, Light Chain, Roadblock Type 1 (DYNLRB1))

Binding Specificity: AA 1-63

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DYNLRB1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Purpose: DYNLRB1 Rabbit pAb

Sequence: MDNPTTTQYA SLMHSFILKA RSTVRDIDPQ NDLTFLRIRS KKNEIMVAPD KDYFLIVIQN PTE

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-63 of human DYNLRB1 (NP_001268656.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for DYNLRB1

Target: DYNLRB1 (Dynein, Light Chain, Roadblock Type 1 (DYNLRB1))

Alternative Name: DYNLRB1 (DYNLRB1 Products)

Synonyms: 2010012N15Rik antibody, 2010320M17Rik antibody, 9430076K19Rik antibody, AV124457 antibody, DNLC2A antibody, Dncl2a antibody, km23-1 antibody, km23 antibody, BITH antibody, BLP antibody, DNCL2A antibody, ROBLD1 antibody, dynein light chain roadblock-type 1 antibody, Dynlrb1 antibody, DYNLRB1 antibody

Background: This gene is a member of the roadblock dynein light chain family. The encoded cytoplasmic protein is capable of binding intermediate chain proteins, interacts with transforming growth factor-beta, and has been implicated in the regulation of actin modulating proteins. Upregulation of this gene has been associated with hepatocellular carcinomas, suggesting that this gene may be involved in tumor progression. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene have been defined on chromosomes 12 and 18.,DYNLRB1,BITH,BLP,DNCL2A,DNLC2A,ROBLD1,Cancer,Tumor biomarkers,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Motor Proteins,DYNLRB1

Molecular Weight: 5kDa/10kDa

Gene ID: 83658

UniProt: Q9NP97