MIB2 antibody (AA 300-580)

Catalog No. ABIN7266881

The Rabbit Polyclonal anti-MIB2 antibody has been validated for WB and IF. It is suitable to detect MIB2 in samples from Human.

Quick Overview for MIB2 antibody (AA 300-580) (ABIN7266881)

Target: MIB2 (E3 ubiquitin-protein ligase MIB2 (MIB2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MIB2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-MIB2 Antibody

Binding Specificity: AA 300-580

Purpose: MIB2 Rabbit pAb

Sequence: ASVTWADGTT NVYRVGHKGK VDLKCVGEAA GGFYYKDHLP RLGKPAELQR RVSADSQPFQ HGDKVKCLLD TDVLREMQEG HGGWNPRMAE FIGQTGTVHR ITDRGDVRVQ FNHETRWTFH PGALTKHHSF WVGDVVRVIG DLDTVKRLQA GHGEWTDDMA PALGRVGKVV KVFGDGNLRV AVAGQRWTFS PSCLVAYRPE EDANLDVAER ARENKSSLSV ALDKLRAQKS DPEHPGRLVV EVALGNAARA LDLLRRRPEQ VDTKNQGRTA LQVAAYLGQV E

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 300-580 of human MIB2 (NP_001164158.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MIB2

Target: MIB2 (E3 ubiquitin-protein ligase MIB2 (MIB2))

Alternative Name: MIB2

Background: The protein encoded by this gene is an E3 ubiquitin protein ligase that mediates ubiquitination of proteins in the Notch signaling pathway. The encoded protein may be a suppressor of melanoma invasion. [provided by RefSeq, Mar 2017],ZZANK1,ZZZ5,MIB2,Cell Biology & Developmental Biology,Notch Signaling Pathway,MIB2

Gene ID: 142678

UniProt: Q96AX9

Pathways: Notch Signaling