EIF4G3 antibody (AA 1000-1200)

Catalog No. ABIN7267044

Product Details anti-EIF4G3 Antibody

Target: EIF4G3 (Eukaryotic Translation Initiation Factor 4 gamma 3 (EIF4G3))

Binding Specificity: AA 1000-1200

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EIF4G3 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: EIF4G3 Rabbit pAb

Sequence: HKEAKIEEQE EQRKVQQLMT KEKRRPGVQR VDEGGWNTVQ GAKNSRVLDP SKFLKITKPT IDEKIQLVPK AQLGSWGKGS SGGAKASETD ALRSSASSLN RFSALQPPAP SGSTPSTPVE FDSRRTLTSR GSMGREKNDK PLPSATARPN TFMRGGSSKD LLDNQSQEEQ RREMLETVKQ LTGGVDVERN STEAERNKTR E

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1000-1200 of human EIF4G3 (NP_003751.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for EIF4G3

Target: EIF4G3 (Eukaryotic Translation Initiation Factor 4 gamma 3 (EIF4G3))

Alternative Name: EIF4G3 (EIF4G3 Products)

Synonyms: eif4g3 antibody, si:dkey-1a7.2 antibody, eIF-4G 3 antibody, eIF4G 3 antibody, eIF4GII antibody, 1500002J22Rik antibody, 4833436O05 antibody, 4930523M17Rik antibody, G1-419-52 antibody, repro8 antibody, eukaryotic translation initiation factor 4 gamma 3 antibody, eukaryotic translation initiation factor 4 gamma, 3 antibody, eukaryotic translation initiation factor 4 gamma, 3b antibody, eukaryotic translation initiation factor 4 gamma, 1 antibody, EIF4G3 antibody, CpipJ_CPIJ009979 antibody, eif4g3 antibody, eif4g3b antibody, eif4g1 antibody, Eif4g3 antibody

Background: The protein encoded by this gene is thought to be part of the eIF4F protein complex, which is involved in mRNA cap recognition and transport of mRNAs to the ribosome. Interestingly, a microRNA (miR-520c-3p) has been found that negatively regulates synthesis of the encoded protein, and this leads to a global decrease in protein translation and cell proliferation. Therefore, this protein is a key component of the anti-tumor activity of miR-520c-3p.,EIF4G3,eIF-4G 3,eIF4G 3,eIF4GII,eIF-4G3,eIF4G3,Epigenetics & Nuclear Signaling,RNA Binding,Translation Control,Regulation of eIF4 and p70 S6 Kinase,EIF4G3

Molecular Weight: 55kDa/146kDa/176kDa/177kDa

Gene ID: 8672

UniProt: O43432