FGF4 antibody (AA 31-206)

Catalog No. ABIN7267187

The Rabbit Polyclonal anti-FGF4 antibody is suitable to detect FGF4 in samples from Human. It has been validated for WB.

Quick Overview for FGF4 antibody (AA 31-206) (ABIN7267187)

Target: FGF4 (Fibroblast Growth Factor 4 (FGF4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FGF4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FGF4 Antibody

Binding Specificity: AA 31-206

Purpose: FGF4 Rabbit pAb

Sequence: APTAPNGTLE AELERRWESL VALSLARLPV AAQPKEAAVQ SGAGDYLLGI KRLRRLYCNV GIGFHLQALP DGRIGGAHAD TRDSLLELSP VERGVVSIFG VASRFFVAMS SKGKLYGSPF FTDECTFKEI LLPNNYNAYE SYKYPGMFIA LSKNGKTKKG NRVSPTMKVT HFLPRL

Cross-Reactivity: Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 31-206 of human FGF4 (NP_001998.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for FGF4

Target: FGF4 (Fibroblast Growth Factor 4 (FGF4))

Alternative Name: FGF4

Background: The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified by its oncogenic transforming activity. This gene and FGF3, another oncogenic growth factor, are located closely on chromosome 11. Co-amplification of both genes was found in various kinds of human tumors. Studies on the mouse homolog suggested a function in bone morphogenesis and limb development through the sonic hedgehog (SHH) signaling pathway.,FGF4,HBGF-4,HST,HST-1,HSTF1,K-FGF,KFGF,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Growth factor,Stem Cells,Cardiovascular,Angiogenesis,FGF4

Molecular Weight: 12kDa/22kDa

Gene ID: 2249

UniProt: P08620

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance