INSIG2 antibody (AA 50-150)

Catalog No. ABIN7267888

This Rabbit Polyclonal antibody specifically detects INSIG2 in WB and IHC. It exhibits reactivity toward Human.

Quick Overview for INSIG2 antibody (AA 50-150) (ABIN7267888)

Target: INSIG2 (Insulin Induced Gene 2 (INSIG2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This INSIG2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-INSIG2 Antibody

Binding Specificity: AA 50-150

Purpose: INSIG2 Rabbit pAb

Sequence: QIQRNVTLFP PDVIASIFSS AWWVPPCCGT ASAVIGLLYP CIDRHLGEPH KFKREWSSVM RCVAVFVGIN HASAKVDFDN NIQLSLTLAA LSIGLWWTFD R

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 50-150 of human INSIG2 (NP_057217.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for INSIG2

Target: INSIG2 (Insulin Induced Gene 2 (INSIG2))

Alternative Name: INSIG2

Background: The protein encoded by this gene is highly similar to the protein product encoded by gene INSIG1. Both INSIG1 protein and this protein are endoplasmic reticulum proteins that block the processing of sterol regulatory element binding proteins (SREBPs) by binding to SREBP cleavage-activating protein (SCAP), and thus prevent SCAP from escorting SREBPs to the Golgi.,INSIG2,INSIG-2,Cancer,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,Cholesterol Metabolism,Cardiovascular,Lipids,INSIG2

Molecular Weight: 24kDa

Gene ID: 51141

UniProt: Q9Y5U4

Pathways: ER-Nucleus Signaling