Integrin Alpha2b antibody

Catalog No. ABIN7267925

The Rabbit Monoclonal anti-Integrin Alpha2b antibody has been validated for WB and IHC. It is suitable to detect Integrin Alpha2b in samples from Human.

Quick Overview for Integrin Alpha2b antibody (ABIN7267925)

Target: Integrin Alpha2b (CD41)

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Integrin Alpha2b antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-Integrin Alpha2b Antibody

Purpose: CD41/ITGA2B Rabbit mAb

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human CD41/ITGA2B

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Integrin Alpha2b

Target: Integrin Alpha2b (CD41)

Alternative Name: ITGA2B

Background: This gene encodes a member of the integrin alpha chain family of proteins. The encoded preproprotein is proteolytically processed to generate light and heavy chains that associate through disulfide linkages to form a subunit of the alpha-IIb/beta-3 integrin cell adhesion receptor. This receptor plays a crucial role in the blood coagulation system, by mediating platelet aggregation. Mutations in this gene are associated with platelet-type bleeding disorders, which are characterized by a failure of platelet aggregation, including Glanzmann thrombasthenia. [provided by RefSeq, Jan 2016],BDPLT16, BDPLT2, CD41, CD41B, GP2B, GPIIb, GT, GTA, HPA3, PPP1R93,Angiogenesis,Blood,Cardiovascular,CDs,Cell Adhesion,Cell Biology & Developmental Biology,Cytoskeleton,G protein signaling,G protein signaling_G-Protein-Coupled Receptors Signaling to MAPK/Erk,Hematopoietic Progenitors,Immunology & Inflammation,MAPK-Erk Signaling Pathway,PI3K-Akt Signaling Pathway,Signal Transduction,Stem Cells,ITGA2B

Molecular Weight: 135kDa

Gene ID: 3674

UniProt: P08514

Pathways: Integrin Complex