LZTS1 antibody (AA 337-596)

Catalog No. ABIN7268226

Product Details anti-LZTS1 Antibody

Target: LZTS1 (Leucine Zipper, Putative Tumor Suppressor 1 (LZTS1))

Binding Specificity: AA 337-596

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LZTS1 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: LZTS1 Rabbit pAb

Sequence: QLQQEKRQLR QELESLMKEQ DLLETKLRSY EREKTSFGPA LEETQWEVCQ KSGEISLLKQ QLKESQTEVN AKASEILGLK AQLKDTRGKL EGLELRTQDL EGALRTKGLE LEVCENELQR KKNEAELLRE KVNLLEQELQ ELRAQAALAR DMGPPTFPED VPALQRELER LRAELREERQ GHDQMSSGFQ HERLVWKEEK EKVIQYQKQL QQSYVAMYQR NQRLEKALQQ LARGDSAGEP LEVDLEGADI PYEDIIATEI

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 337-596 of human LZTS1 (NP_066300.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for LZTS1

Target: LZTS1 (Leucine Zipper, Putative Tumor Suppressor 1 (LZTS1))

Alternative Name: LZTS1 (LZTS1 Products)

Synonyms: F37 antibody, FEZ1 antibody, Psdzip70 antibody, LZTS1 antibody, f37 antibody, fez1 antibody, leucine zipper tumor suppressor 1 antibody, leucine zipper, putative tumor suppressor 1 antibody, LZTS1 antibody, Lzts1 antibody, lzts1 antibody

Background: This gene encodes a tumor suppressor protein that is ubiquitously expressed in normal tissues. In uveal melanomas, expression of this protein is silenced in rapidly metastasizing and metastatic tumor cells but has normal expression in slowly metastasizing or nonmetastasizing tumor cells. This protein may have a role in cell-cycle control by interacting with the Cdk1/cyclinB1 complex. This gene is located on chromosomal region 8p22. Loss of heterozygosity (LOH) in the 8p arm is a common characteristic of many types of cancer.,LZTS1,F37,FEZ1,Epigenetics & Nuclear Signaling,Transcription Factors,Cancer,Tumor suppressors,Cell Biology & Developmental Biology,Cell Cycle,Cell cycle inhibitors,LZTS1

Molecular Weight: 8kDa/22kDa/55kDa/59kDa/62kDa/63kDa/66kDa

Gene ID: 11178

UniProt: Q9Y250

Pathways: Synaptic Membrane