GNPTAB antibody (AA 42-350)

Catalog No. ABIN7268770

Product Details anti-GNPTAB Antibody

Target: GNPTAB (N-Acetylglucosamine-1-Phosphate Transferase, alpha and beta Subunits (GNPTAB))

Binding Specificity: AA 42-350

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GNPTAB antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: GNPTAB Rabbit pAb

Sequence: LEWSRDQYHV LFDSYRDNIA GKSFQNRLCL PMPIDVVYTW VNGTDLELLK ELQQVREQME EEQKAMREIL GKNTTEPTKK SEKQLECLLT HCIKVPMLVL DPALPANITL KDLPSLYPSF HSASDIFNVA KPKNPSTNVS VVVFDSTKDV EDAHSGLLKG NSRQTVWRGY LTTDKEVPGL VLMQDLAFLS GFPPTFKETN QLKTKLPENL SSKVKLLQLY SEASVALLKL NNPKDFQELN KQTKKNMTID GKELTISPAY LLWDLSAISQ SKQDEDISAS RFEDNEELRY SLRSIERHAP WVRNIFIVT

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 42-350 of human GNPTAB (NP_077288.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for GNPTAB

Target: GNPTAB (N-Acetylglucosamine-1-Phosphate Transferase, alpha and beta Subunits (GNPTAB))

Alternative Name: GNPTAB (GNPTAB Products)

Synonyms: si:ch211-234f20.3 antibody, wu:fd55d09 antibody, zgc:122985 antibody, zgc:158502 antibody, GNPTA antibody, ICD antibody, EG432486 antibody, mKIAA1208 antibody, RGD1564821 antibody, N-acetylglucosamine-1-phosphate transferase alpha and beta subunits antibody, N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits antibody, N-acetylglucosamine-1-phosphotransferase subunits alpha/beta antibody, GNPTAB antibody, gnptab antibody, LOC100175423 antibody, Gnptab antibody

Background: This gene encodes two of three subunit types of the membrane-bound enzyme N-acetylglucosamine-1-phosphotransferase, a heterohexameric complex composed of two alpha, two beta, and two gamma subunits. The encoded protein is proteolytically cleaved at the Lys928-Asp929 bond to yield mature alpha and beta polypeptides while the gamma subunits are the product of a distinct gene (GeneID 84572). In the Golgi apparatus, the heterohexameric complex catalyzes the first step in the synthesis of mannose 6-phosphate recognition markers on certain oligosaccharides of newly synthesized lysosomal enzymes. These recognition markers are essential for appropriate trafficking of lysosomal enzymes. Mutations in this gene have been associated with both mucolipidosis II and mucolipidosis IIIA.,GNPTAB,GNPTA,ICD,Cancer,Signal Transduction,Endocrine & Metabolism,GNPTAB

Molecular Weight: 55kDa/143kDa

Gene ID: 79158

UniProt: Q3T906