PPT1 antibody (AA 28-306)
Quick Overview for PPT1 antibody (AA 28-306) (ABIN7269164)
Target
See all PPT1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 28-306
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Purpose
- PPT1 Rabbit pAb
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Sequence
- DPPAPLPLVI WHGMGDSCCN PLSMGAIKKM VEKKIPGIYV LSLEIGKTLM EDVENSFFLN VNSQVTTVCQ ALAKDPKLQQ GYNAMGFSQG GQFLRAVAQR CPSPPMINLI SVGGQHQGVF GLPRCPGESS HICDFIRKTL NAGAYSKVVQ ERLVQAEYWH DPIKEDVYRN HSIFLADINQ ERGINESYKK NLMALKKFVM VKFLNDSIVD PVDSEWFGFY RSGQAKETIP LQETSLYTQD RLGLKEMDNA GQLVFLATEG DHLQLSEEWF YAHIIPFLG
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Cross-Reactivity
- Human, Mouse, Rat
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Characteristics
- Polyclonal Antibodies
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Purification
- Affinity purification
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 28-306 of human PPT1 (NP_000301.1).
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Isotype
- IgG
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Application Notes
- WB,1:500 - 1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- PPT1 (Palmitoyl-Protein Thioesterase 1 (PPT1))
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Alternative Name
- PPT1
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Background
- The protein encoded by this gene is a small glycoprotein involved in the catabolism of lipid-modified proteins during lysosomal degradation. The encoded enzyme removes thioester-linked fatty acyl groups such as palmitate from cysteine residues. Defects in this gene are a cause of infantile neuronal ceroid lipofuscinosis 1 (CLN1, or INCL) and neuronal ceroid lipofuscinosis 4 (CLN4). Two transcript variants encoding different isoforms have been found for this gene.,PPT1,CLN1,INCL,PPT,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Endocrine & Metabolism,Lipid Metabolism,PPT1
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Molecular Weight
- 23kDa/34kDa
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Gene ID
- 5538
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UniProt
- P50897
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Pathways
- SARS-CoV-2 Protein Interactome
Target
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