Prostaglandin E Synthase antibody

Catalog No. ABIN7269573

Product Details anti-Prostaglandin E Synthase Antibody

Target: Prostaglandin E Synthase (PTGES)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Prostaglandin E Synthase antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Purpose: PTGES Rabbit pAb

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide of human PTGES.

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Prostaglandin E Synthase

Target: Prostaglandin E Synthase (PTGES)

Alternative Name: PTGES (PTGES Products)

Synonyms: ptges antibody, MGC80290 antibody, PTGES antibody, MGST-IV antibody, MGST1-L1 antibody, MGST1L1 antibody, MPGES antibody, PGES antibody, PIG12 antibody, PP102 antibody, PP1294 antibody, TP53I12 antibody, mPGES-1 antibody, 2410099E23Rik antibody, D2Ertd369e antibody, Pges antibody, mPGES antibody, MPGES-1 antibody, prostaglandin E synthase antibody, prostaglandin E synthase S homeolog antibody, PTGES antibody, ptges.S antibody, Ptges antibody

Background: The protein encoded by this gene is a glutathione-dependent prostaglandin E synthase. The expression of this gene has been shown to be induced by proinflammatory cytokine interleukin 1 beta (IL1B). Its expression can also be induced by tumor suppressor protein TP53, and may be involved in TP53 induced apoptosis. Knockout studies in mice suggest that this gene may contribute to the pathogenesis of collagen-induced arthritis and mediate acute pain during inflammatory responses.,PTGES, MGST-IV, MGST1-L1, MGST1L1, MPGES, PGES, PIG12, PP102, PP1294, TP53I12, mPGES-1, prostaglandin E synthase,Cell Intrinsic Innate Immunity Signaling Pathway,Immunology & Inflammation,Signal Transduction,PTGES

Molecular Weight: 17kDa

Gene ID: 9536

UniProt: O14684