PTPRD antibody (AA 1100-1265)
Quick Overview for PTPRD antibody (AA 1100-1265) (ABIN7269708)
Target
See all PTPRD AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 1100-1265
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Purpose
- PTPRD Rabbit pAb
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Sequence
- TAKTAPDVLR TKPAFIGKTN LDGMITVQLP EVPANENIKG YYIIIVPLKK SRGKFIKPWE SPDEMELDEL LKEISRKRRS IRYGREVELK PYIAAHFDVL PTEFTLGDDK HYGGFTNKQL QSGQEYVFFV LAVMEHAESK MYATSPYSDP VVSMDLDPQP ITDEEE
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Cross-Reactivity
- Human, Mouse, Rat
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Characteristics
- Polyclonal Antibodies
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Purification
- Affinity purification
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 1100-1265 of human PTPRD (NP_002830.1).
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Isotype
- IgG
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Application Notes
- WB,1:500 - 1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- PTPRD (Protein tyrosine Phosphatase, Receptor Type, D (PTPRD))
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Alternative Name
- PTPRD
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Background
- The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this protein is composed of three Ig-like and eight fibronectin type III-like domains. Studies of the similar genes in chicken and fly suggest the role of this PTP is in promoting neurite growth, and regulating neurons axon guidance. Multiple alternatively spliced transcript variants of this gene have been reported. A related pseudogene has been identified on chromosome 5.,PTPRD,HPTP,HPTPD,HPTPDELTA,PTPD,RPTPDELTA,Signal Transduction,Neuroscience,PTPRD
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Molecular Weight
- 156kDa/169kDa/212kDa/214kDa
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Gene ID
- 5789
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UniProt
- P23468
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Pathways
- Synaptic Membrane
Target
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