RMND5A antibody (AA 200-270)

Catalog No. ABIN7269917

Product Details anti-RMND5A Antibody

Target: RMND5A (Required For Meiotic Nuclear Division 5 Homolog A (RMND5A))

Binding Specificity: AA 200-270

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RMND5A antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: RMND5A Rabbit pAb

Sequence: ISLLMGGTTN QREALQYAKN FQPFALNHQK DIQVLMGSLV YLRQGIENSP YVHLLDANQW ADICDIFTRD A

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 200-270 of human RMND5A (NP_073617.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for RMND5A

Target: RMND5A (Required For Meiotic Nuclear Division 5 Homolog A (RMND5A))

Alternative Name: RMND5A (RMND5A Products)

Synonyms: CTLH antibody, GID2 antibody, GID2A antibody, RMD5 antibody, p44CTLH antibody, 1110007A06Rik antibody, AJ237586 antibody, AW125795 antibody, Gid2 antibody, MTA.D02.090 antibody, required for meiotic nuclear division 5 homolog A antibody, RMND5A antibody, Rmnd5a antibody

Background: Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1. MAEA and RMND5A are both required for catalytic activity of the CTLH E3 ubiquitin-protein ligase complex. Catalytic activity of the complex is required for normal cell proliferation. The CTLH E3 ubiquitin-protein ligase complex is not required for the degradation of enzymes involved in gluconeogenesis, such as FBP1.,RMND5A,CTLH,GID2,GID2A,RMD5,p44CTLH,Cell Biology & Developmental Biology,Cytoskeleton,Microtubules,RMND5A

Molecular Weight: 10kDa/43kDa

Gene ID: 64795

UniProt: Q9H871