SSTR5 antibody

Catalog No. ABIN7270495

This Rabbit Monoclonal antibody specifically detects SSTR5 in WB, IHC and IHC (p). It exhibits reactivity toward Human.

Quick Overview for SSTR5 antibody (ABIN7270495)

Target: SSTR5 (Somatostatin Receptor 5 (SSTR5))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This SSTR5 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-SSTR5 Antibody

Purpose: SSTR5 Rabbit mAb

Sequence: MEPLFPAST PSWNASSPGAAS GGGDNRTLVGPAPSAGAR AVLVPVLYLLVCAAGLG GNTLVIYVVLRFAKM KTVTNIYILNLAVAD VLYMLGLPFLATQN

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human SSTR5 (P35346).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SSTR5

Target: SSTR5 (Somatostatin Receptor 5 (SSTR5))

Alternative Name: SSTR5

Background: Somatostatin and its related peptide cortistatin exert multiple biological actions on normal and tumoral tissue targets by interacting with somatostatin receptors (SSTRs). The protein encoded by this gene is one of the SSTRs, which is a multi-pass membrane protein and belongs to the G-protein coupled receptor 1 family. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase, and different regions of this receptor molecule are required for the activation of different signaling pathways. A mutation in this gene results in somatostatin analog resistance. Alternatively spliced transcript variants have been identified in this gene.[provided by RefSeq, Feb 2010],SS-5-R,G protein signaling,G protein signaling_G-Protein-Coupled Receptors(GPCR),Neuroscience,Signal Transduction,SSTR5

Molecular Weight: 42kDa

Gene ID: 6755

UniProt: P35346

Pathways: Carbohydrate Homeostasis