SSTR5 antibody

Catalog No. ABIN7862552

This Rabbit Polyclonal antibody specifically detects SSTR5 in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for SSTR5 antibody (ABIN7862552)

Target: SSTR5 (Somatostatin Receptor 5 (SSTR5))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SSTR5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-SSTR5 Antibody

Purpose: Rabbit Anti-SSR5 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of SSR5 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human SSR5 protein at AA range: 270-350

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for SSTR5

Target: SSTR5 (Somatostatin Receptor 5 (SSTR5))

Alternative Name: SSR5

Background: Somatostatin receptor type 5, SS-5-R, SS5-R, SS5RSomatostatin and its related peptide cortistatin exert multiple biological actions on normal and tumoral tissue targets by interacting with somatostatin receptors (SSTRs). The protein encoded by SSTR5 is one of the SSTRs, which is a multi-pass membrane protein and belongs to the G-protein coupled receptor 1 family. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase, and different regions of this receptor molecule are required for the activation of different signaling pathways. A mutation in SSTR5 results in somatostatin analog resistance. Alternatively spliced transcript variants have been identified in SSTR5.

Molecular Weight: 40kD

Gene ID: 6755

UniProt: P35346

Pathways: Carbohydrate Homeostasis