SHB antibody (AA 300-400)

Catalog No. ABIN7270563

Product Details anti-SHB Antibody

Target: SHB (Src Homology 2 Domain Containing Adaptor Protein B (SHB))

Binding Specificity: AA 300-400

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SHB antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: SHB Rabbit pAb

Sequence: PYEPEGQSVD SDSESTVSPR LRESKLPQDD DRPADEYDQP WEWNRVTIPA LAAQFNGNEK RQSSPSPSRD RRRQLRAPGG GFKPIKHGSP EFCGILGERV D

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 300-400 of human SHB (NP_003019.2).

Isotype: IgG

Application Details

Application Notes: WB,1:200 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SHB

Target: SHB (Src Homology 2 Domain Containing Adaptor Protein B (SHB))

Alternative Name: SHB (SHB Products)

Synonyms: SHB antibody, RP11-3J10.8 antibody, bA3J10.2 antibody, RGD1565350 antibody, BC028832 antibody, SH2 domain containing adaptor protein B antibody, src homology 2 domain-containing transforming protein B antibody, SHB antibody, Shb antibody

Background: Adapter protein which regulates several signal transduction cascades by linking activated receptors to downstream signaling components. May play a role in angiogenesis by regulating FGFR1, VEGFR2 and PDGFR signaling. May also play a role in T-cell antigen receptor/TCR signaling, interleukin-2 signaling, apoptosis and neuronal cells differentiation by mediating basic-FGF and NGF-induced signaling cascades. May also regulate IRS1 and IRS2 signaling in insulin-producing cells.,SHB,bA3J10.2,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Stem Cells,Embryonic Stem Cells,Cardiovascular,Angiogenesis,SHB

Molecular Weight: 30kDa/55kDa

Gene ID: 6461

UniProt: Q15464