SDHD antibody (AA 50-150)

Catalog No. ABIN7270622

The Rabbit Polyclonal anti-SDHD antibody is suitable to detect SDHD in samples from Human. It has been validated for WB.

Quick Overview for SDHD antibody (AA 50-150) (ABIN7270622)

Target: SDHD (Succinate Dehydrogenase Complex, Subunit D, Integral Membrane Protein (SDHD))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SDHD antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SDHD Antibody

Binding Specificity: AA 50-150

Purpose: SDHD Rabbit pAb

Sequence: HLSPSHHSGS KAASLHWTSE RVVSVLLLGL LPAAYLNPCS AMDYSLAAAL TLHGHWGLGQ VVTDYVHGDA LQKAAKAGLL ALSALTFAGL CYFNYHDVGI C

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 50-150 of human SDHD (NP_002993.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SDHD

Target: SDHD (Succinate Dehydrogenase Complex, Subunit D, Integral Membrane Protein (SDHD))

Alternative Name: SDHD

Background: This gene encodes a member of complex II of the respiratory chain, which is responsible for the oxidation of succinate. The encoded protein is one of two integral membrane proteins anchoring the complex to the matrix side of the mitochondrial inner membrane. Mutations in this gene are associated with the formation of tumors, including hereditary paraganglioma. Transmission of disease occurs almost exclusively through the paternal allele, suggesting that this locus may be maternally imprinted. There are pseudogenes for this gene on chromosomes 1, 2, 3, 7, and 18. Alternative splicing results in multiple transcript variants.,SDHD,CBT1,CII-4,CWS3,PGL,PGL1,QPs3,SDH4,cybS,Cancer,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Oxidative phosphorylation,Neuroscience,Neurodegenerative Diseases,SDHD

Molecular Weight: 9kDa/12kDa/15kDa/17kDa

Gene ID: 6392

UniProt: O14521