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- Target See all TET2 Antibodies
- TET2 (Tet Methylcytosine Dioxygenase 2 (TET2))
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Reactivity
- Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TET2 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (IF)
- Purpose
- TET2 Rabbit pAb
- Cross-Reactivity
- Human, Mouse, Rat
- Characteristics
- Polyclonal Antibodies
- Purification
- Affinity purification
- Immunogen
- Recombinant protein of mouse TET2.
- Isotype
- IgG
- Top Product
- Discover our top product TET2 Primary Antibody
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anti-Tet Methylcytosine Dioxygenase 2 (TET2) (AA 1833-2002) antibody
TET2 Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Tet Methylcytosine Dioxygenase 2 (TET2) antibodyTET2 Reactivity: Human WB, ELISA, IHC, FACS, ICC Host: Mouse Monoclonal 5H8C7 unconjugated
anti-Tet Methylcytosine Dioxygenase 2 (TET2) antibodyTET2 Reactivity: Human, Mouse, Rat WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Tet Methylcytosine Dioxygenase 2 (TET2) antibodyTET2 Reactivity: Human WB, ELISA, FACS Host: Mouse Monoclonal 5H8B3 unconjugated
anti-Tet Methylcytosine Dioxygenase 2 (TET2) (AA 1833-2002) antibodyTET2 Reactivity: Human ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Tet Methylcytosine Dioxygenase 2 (TET2) (AA 528-554), (N-Term) antibodyTET2 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB37907 unconjugated
anti-Tet Methylcytosine Dioxygenase 2 (TET2) (Internal Region) antibodyVerified TET2 Reactivity: Human ELISA, IHC, FACS Host: Goat Polyclonal unconjugated
anti-Tet Methylcytosine Dioxygenase 2 (TET2) (AA 1-300) antibodyTET2 Reactivity: Human WB, IP Host: Mouse Monoclonal 21F11 unconjugated
anti-Tet Methylcytosine Dioxygenase 2 (TET2) (Internal Region) antibodyRecent TET2 Reactivity: Mouse, Rat ELISA Host: Goat Polyclonal unconjugated
anti-Tet Methylcytosine Dioxygenase 2 (TET2) (N-Term) antibodyTET2 Reactivity: Human WB, ELISA Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB,1:500 - 1:2000,IF,1:50 - 1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- TET2 (Tet Methylcytosine Dioxygenase 2 (TET2))
- Alternative Name
- TET2 (TET2 Products)
- Synonyms
- KIAA1546 antibody, MDS antibody, Ayu17-449 antibody, E130014J05Rik antibody, mKIAA1546 antibody, RGD1311625 antibody, tet methylcytosine dioxygenase 2 antibody, TET2 antibody, Tet2 antibody
- Background
- Dioxygenase that catalyzes the conversion of the modified genomic base 5-methylcytosine (5mC into 5-hydroxymethylcytosine (5hmC and plays a key role in active DNA demethylation. Has a preference for 5-hydroxymethylcytosine in CpG motifs. Also mediates subsequent conversion of 5hmC into 5-formylcytosine (5fC, and conversion of 5fC to 5-carboxylcytosine (5caC. Conversion of 5mC into 5hmC, 5fC and 5caC probably constitutes the first step in cytosine demethylation. Methylation at the C5 position of cytosine bases is an epigenetic modification of the mammalian genome which plays an important role in transcriptional regulation. In addition to its role in DNA demethylation, also involved in the recruitment of the O-GlcNAc transferase OGT to CpG-rich transcription start sites of active genes, thereby promoting histone H2B GlcNAcylation by OGT.,Ayu17-44, Ayu17-449, mKIAA1546, E130014J05Rik,TET2
- Molecular Weight
- 212kDa
- Gene ID
- 214133
- UniProt
- Q4JK59
- Pathways
- Warburg Effect
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