Integrin Alpha2b antibody

Catalog No. ABIN7271758

This Mouse Monoclonal antibody specifically detects Integrin Alpha2b in FACS. It exhibits reactivity toward Human.

Quick Overview for Integrin Alpha2b antibody (ABIN7271758)

Target: Integrin Alpha2b (CD41)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Integrin Alpha2b antibody is un-conjugated

Application: Flow Cytometry (FACS)

Grade: GMP Grade

Clone: 962C1

Product Details anti-Integrin Alpha2b Antibody

Purpose: CD41a Unconjugated Antibody

Characteristics: The clone 962C1, a mouse monoclonal antibody, reacts with the human CD41 Molecule, the integrin alpha-IIb also known as platelet GPIIb. CD41 is composed of two subunits GPIIbα (120 kDa) and GPIIbβ (23  kDa) that interact with CD61 to form a functional protein receptor in the presence of calcium. This protein receptor involves in the blood coagulation system, by mediating platelet adhesion and aggregation. Upon blood vessel damage, CD41 binds to a variety of proteins like von Willebrand factor, fibrinogen, fibronectin and vitronectin. CD41 is mainly expressed on megakaryocytes and platelets. Diseases associated with CD41 dysfunction include Glansmann Thrombasthenia, and Platelet type-16 bleeding disorder

Purification: Purified

Purity: >95 %

Immunogen: Recombinant full-length human Integrin alpha IIb protein

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS pH 7.2, 0.1 % (w/v) BSA, 0.09 % (w/v) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Target Details for Integrin Alpha2b

Target: Integrin Alpha2b (CD41)

Alternative Name: CD41a

Gene ID: 3674

UniProt: P08514

Pathways: Integrin Complex