CD47 antibody

Catalog No. ABIN7271949

This anti-CD47 antibody is a Mouse Monoclonal antibody detecting CD47 in FACS. Suitable for Human.

Quick Overview for CD47 antibody (ABIN7271949)

Target: CD47

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD47 antibody is un-conjugated

Application: Flow Cytometry (FACS)

Grade: GMP Grade

Clone: B6H12-2

Product Details anti-CD47 Antibody

Purpose: CD47 Unconjugated Antibody

Characteristics: The clone B6H12, a mouse monoclonal antibody selectively recognizes a ~50 kDa N-linked glycan protein originally known as integrin-associated protein or IAP and currently known as CD47. CD47 is an unusual Immunoglobulin (Ig) family member, with an Ig variable-like amino-terminal extracellular domain and a five times membrane-spanning carboxyl-terminal region. It is broadly expressed on the plasma membranes of all hematopoietic cells, including erythrocytes. CD47 plays various important roles in cellular functional processes, including proliferation, apoptosis, adhesion, migration, and also in immune regulation and homeostasis. CD47 is highly expressed on myeloma cells and may be considered as a potential therapeutic candidate for myeloma therapy.

Purification: Purified

Purity: >95 %

Immunogen: Intact CD47 purified from placenta

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS pH 7.2, 0.1 % (w/v) BSA, 0.09 % (w/v) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Target Details for CD47

Target: CD47

Alternative Name: CD47

Gene ID: 961

UniProt: Q08722