Integrin beta 2 antibody (N-Term)

Catalog No. ABIN7273029

The Goat Polyclonal anti-Integrin beta 2 antibody is suitable to detect Integrin beta 2 in samples from Human, Mouse, Rat, Dog and Monkey. It has been validated for WB.

Quick Overview for Integrin beta 2 antibody (N-Term) (ABIN7273029)

Target: Integrin beta 2 (ITGB2)

Reactivity: Human, Mouse, Rat, Dog, Monkey

Host: Goat

Clonality: Polyclonal

Conjugate: This Integrin beta 2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Integrin beta 2 Antibody

Binding Specificity: N-Term

Purpose: Anti-ITGB2

Sequence: MLGLRPPLLA LVGLLSLGCV LSQECTKFKV SSCRECIESG PGCTWCQKLN FTGPGDPDSI RCDTRPQLLM RGCAADDIMD PTSLAETQED HNGGQKQLSP QKVTLYLRPG QAAAFNVTFR RAKGYPIDLY YLMDLS

Specificity: Detects endogenous levels of ITGB2 using Jurkat cell line by Western blot.

Cross-Reactivity (Details): Reacts against human, rat, mouse, canine and monkey proteins

Purification: Epitope affinity purified

Immunogen: Recombinant peptide derived from within residues 140 aa to the N-terminus of human ITGB2 produced in E. coli.

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:2,000

Restrictions: For Research Use only

Handling

Concentration: 3 mg/mL

Buffer: PBS, 20 % glycerol and 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: The antibody solution should be gently mixed before use.

Storage: 4 °C,-20 °C

Storage Comment: For continuous use, store at 2-8 C for one-two days. For extended storage, store in -20 C freezer. Working dilution samples should be discarded if not used within 12 hours.

Target Details for Integrin beta 2

Target: Integrin beta 2 (ITGB2)

Alternative Name: ITGB2

Background:

Goat polyclonal antibody to ITGB2. The integrin beta chain combined with multiple different alpha chains form different integrin heterodimers. Integrins are integral cell-surface proteins that act as cell-surface mediated signaling and participate in cell adhesion.

CD18, LAD, LCAMB, LFA-1, MAC-1, MF17, MFI7 antibody.

Pathways: NF-kappaB Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation