ZIKV E antibody

Catalog No. ABIN7383930

Product Details anti-ZIKV E Antibody

Target: ZIKV E (Zika Virus Envelope (ZIKV E))

Reactivity: Zika Virus (ZIKV)

Host: Rabbit

Clonality: Monoclonal

Conjugate: This ZIKV E antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: Anti-Zika virus(ZIKV)(strain Zika SPH2015) ZIKV-E/Envelope protein(Domain III) Monoclonal Antibody

Purification: Protein A Affinity

Immunogen: Recombinant ZIKV (strain Zika SPH2015) Envelope protein (Domain III, His Tag), ABIN7198753

Clone: 29

Isotype: IgG

Application Details

Application Notes: WB 1:2000-1:10000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: 0.2 μm filtered solution in PBS

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ZIKV E

Target: ZIKV E (Zika Virus Envelope (ZIKV E))

Alternative Name: ZIKV Envelope Protein (ZIKV E Products)

Background: E,Envelope Protein,Envelope of Zika virus is resposible for receptor binding and membrane. Analysis of the envelope protein of Zika, from Brazilian Zika SPH215 (KU321639), indicates predicted B and T cell epitopes in peptides that are consistent to those reported for dengue, YFYF and Japanese encephalitis. The envelope Domain II B cell epitope, to which much dengue non-neutralizing cross reaction is attributed, is also conserved also in Zika virus, consistent with prior field observations of cross reactivity with dengue and YF. Domain III of the Zika envelope protein, likely the main specific neutralizing domain, is distinct from recent Brazilian dengue isolates and a recent Peruvian YF isolate (GQ379163), 76 % of possible major histocompatibility complex class (MHC) I and MHC II binding peptides and potential B cell linear epitopes are unique to Zika virus.