Aurora A antibody (pThr288)

Catalog No. ABIN7448381

The Rabbit Polyclonal anti-Aurora A antibody has been validated for IF/ICC. It is suitable to detect Aurora A in samples from Human.

Quick Overview for Aurora A antibody (pThr288) (ABIN7448381)

Target: Aurora A (AURKA) (Aurora Kinase A (AURKA))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Aurora A antibody is un-conjugated

Application: Immunofluorescence (fixed cells) (IF/ICC)

Product Details anti-Aurora A Antibody

Binding Specificity: pThr288

Purpose: Rabbit anti-Phospho Aurora A (T288) IHC Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: Surrounding threonine 288

Isotype: IgG

Application Details

Application Notes: 1:100 - 1:500

Restrictions: For Research Use only

Handling

Concentration: 250 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for Aurora A

Target: Aurora A (AURKA) (Aurora Kinase A (AURKA))

Alternative Name: Aurora A

Background: Background: Aurora A is a serine-threonine protein kinase that localizes to centrosomes and spindle poles and is important to spindle assembly and chromosome congression. Substrates of Aurora A kinase activity include BRCA1, CDC25B, and NDEL1. Aurora A has been found to be overexpressed in human cancers.

Gene ID: 6790

NCBI Accession: NP_003591

UniProt: O14965

Pathways: Cell Division Cycle, Asymmetric Protein Localization