CDK2 antibody (AA 248-298)
Quick Overview for CDK2 antibody (AA 248-298) (ABIN7448471)
Target
See all CDK2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 248-298
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Purpose
- Rabbit anti-CDK2 IHC Antibody, Affinity Purified
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Predicted Reactivity
- Rat,Sheep,Goat,Bovine,Dog,Horse,Rabbit,Pig,Golden hamster,Panda,Orangutan,Monkey,Gorilla,Chimpanzee,African elephant,Black rat,Small-eared galago,Northern white-cheeked gibbon,Chinese hamster,Thirteen-lined ground squirrel,White-tufted-ear marmoset,Little brown bat,Crab-eating macaque
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Purification
- Affinity Purified
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Immunogen
- Between AA 248 and 298
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Isotype
- IgG
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Application Notes
- 1:100 - 1:500
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Restrictions
- For Research Use only
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Concentration
- 250 μg/mL
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Buffer
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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Expiry Date
- 12 months
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- CDK2 (Cyclin-Dependent Kinase 2 (CDK2))
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Alternative Name
- CDK2
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Background
- Background: Cyclin-dependent kinase 2 (CDK2) is a member of the CDK family of protein kinases that regulate cell cycle progression. CDK2 associates with cyclin E or cyclin A to drive the cell cycle through G1- and S-phase. Substrates of CDK2 include pRb, p53, p27, E2F, Brca1, CDK7, B-Myb, PP1 alpha, RNA Pol II CTD, axin, p220 NPAT, ribonucleotide reductase M2, Myo-D, MARCKS, HsCdc6, and CP110.
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Gene ID
- 1017
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NCBI Accession
- NP_001789
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UniProt
- P24941
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Pathways
- PI3K-Akt Signaling, Cell Division Cycle, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA
Target
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