Cyclin C antibody (AA 244-294)

Catalog No. ABIN7448506

This Rabbit Polyclonal antibody specifically detects Cyclin C in IHC. It exhibits reactivity toward Human.

Quick Overview for Cyclin C antibody (AA 244-294) (ABIN7448506)

Target: Cyclin C (CCNC)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cyclin C antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-Cyclin C Antibody

Binding Specificity: AA 244-294

Purpose: Rabbit anti-Cyclin C IHC Antibody, Affinity Purified

Predicted Reactivity: Mouse,Rat,Chicken,Turkey,Bovine,Dog,Horse,Rabbit,Guinea pig_10141,Pig,Panda,Orangutan,Monkey,Gorilla,Chimpanzee,African elephant,Tasmanian devil,White-tufted-ear marmoset,Small-eared galago,Little brown bat,Naked mole rat,Thirteen-lined ground squirrel,Chinese hamster,Crab-eating macaque,Duckbill platypus,Gray short-tailed opossum,Zebra finch,Northern white-cheeked gibbon

Purification: Affinity Purified

Immunogen: Between AA 244 and 294

Isotype: IgG

Application Details

Application Notes: 1:100 - 1:500

Restrictions: For Research Use only

Handling

Concentration: 100 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for Cyclin C

Target: Cyclin C (CCNC)

Alternative Name: Cyclin C

Background: Background: Cyclin C is a member of the cyclin family of regulatory proteins that associate with and activate cyclin-dependent kinases (CDKs) to regulate cell cycle progression. Cyclins exhibit periodicity in their expression and activity which is regulated transcriptionally and post-transcriptionally via phosphorylation and ubiquitination. Cyclin C associates with cyclin-dependent kinase 8 (CDK8). It is also a component of the Mediator complex, a coactivator complex that provides a scaffold to link gene-specific transcription factors to RNA polymerase II and the general transcription machinery.

Gene ID: 892

NCBI Accession: NP_005181

UniProt: P24863

Pathways: Cell Division Cycle, Regulation of Lipid Metabolism by PPARalpha