DDX21 antibody (C-Term)

Catalog No. ABIN7448516

The Rabbit Polyclonal anti-DDX21 antibody has been validated for IHC. It is suitable to detect DDX21 in samples from Human and Mouse.

Quick Overview for DDX21 antibody (C-Term) (ABIN7448516)

Target: DDX21 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 21 (DDX21))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DDX21 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-DDX21 Antibody

Binding Specificity: C-Term

Purpose: Rabbit anti-DDX21 IHC Antibody, Affinity Purified

Predicted Reactivity: Rat,Dog,Horse,Pig,Panda,Orangutan,Monkey,Gorilla,Chimpanzee,Northern white-cheeked gibbon,Thirteen-lined ground squirrel,Crab-eating macaque,African elephant

Purification: Affinity Purified

Immunogen: Between AA 725 and C-term

Isotype: IgG

Application Details

Application Notes: 1:100 - 1:500

Restrictions: For Research Use only

Handling

Concentration: 250 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for DDX21

Target: DDX21 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 21 (DDX21))

Alternative Name: DDX21

Background: Background: DDX21 is a member of the DEAD box family of proteins that possesses several conserved motifs which include the highly conserved DEAD (Asp-Glu-Ala-Asp) amino acid sequence motif. The major activity of DEAD box proteins is to function as ATP-dependent RNA helicases. As helicases, DEAD proteins play an important role in all aspects of RNA metabolism and function which include pre-mRNA splicing, RNA synthesis, RNA degradation, RNA export, RNA translation, RNA secondary structure formation, ribosome biogenesis, and the assembly of RNP complexes. Some members of the DEAD box proteins also exhibit functions involved in transcriptional regulation. DDX21 has been shown to be required for the processing of 20S rRNA to 18S and has also been shown to be important for c-Jun transcriptional activation.

Gene ID: 9188

NCBI Accession: NP_004719

UniProt: Q9NR30

Pathways: SARS-CoV-2 Protein Interactome