TFIIIC antibody, TFIIIC220 antibody, TFIIICalpha antibody, general transcription factor III C 1 antibody, general transcription factor IIIC subunit 1 antibody, Gtf3c1 antibody, GTF3C1 antibody
Background
Background: General transcription factor 3C polypeptide 1 (GTF3C1/TFIIIC220) is a subunit of the TFIIIC DNA-binding factor required for transcription of tRNA and 5S rRNA genes by RNA polymerase III. Human TFIIIC is composed of six subunits: TFIIIC220, TFIIIC110, TFIIIC102, TFIIIC90 and TFIIIC63, and TFIIIC35. The functional contribution of GTF3C1/TFIIIC220 to the TFIIIC complex has not been fully determined.