General Transcription Factor 3C Polypeptide 3 (GTF3C3) (AA 475-525) antibody

Catalog No. ABIN7448586

The Rabbit Polyclonal anti-General Transcription Factor 3C Polypeptide 3 antibody (ABIN7448586) specifically detects General Transcription Factor 3C Polypeptide 3 in IHC. The antibody is reactive with Human samples.

Quick Overview for General Transcription Factor 3C Polypeptide 3 (GTF3C3) (AA 475-525) antibody (ABIN7448586)

Target: General Transcription Factor 3C Polypeptide 3 (GTF3C3)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Immunohistochemistry (IHC)

Product Details

Binding Specificity: AA 475-525

Purpose: Rabbit anti-GTF3C3/TFIII1C102 IHC Antibody, affinity purified

Predicted Reactivity: Mouse,Rat,X. tropicalis,Bovine,Dog,Horse,Rabbit,Guinea pig_10141,Pig,Panda,Orangutan,Monkey,Gorilla,Chimpanzee,Chinese hamster,Crab-eating macaque,African elephant,Ferret,Little brown bat,Zebra finch,Naked mole rat,Green anole,Northern white-cheeked gibbon,Tasmanian devil,White-tufted-ear marmoset,Gray short-tailed opossum,Small-eared galago

Purification: Affinity Purified

Immunogen: Between AA 475 and 525

Isotype: IgG

Application Details

Application Notes: 1:100 - 1:500

Restrictions: For Research Use only

Handling

Concentration: 100 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details

Target: General Transcription Factor 3C Polypeptide 3 (GTF3C3)

Alternative Name: GTF3C3/TFIIIC102

Background: Background: General transcription factor 3C polypeptide 3 (GTF3C3/TFIIIC102) is a subunit of the TFIIIC DNA-binding factor required for transcription of tRNA and 5S rRNA genes by RNA polymerase III. Human TFIIIC is composed of six subunits: TFIIIC220, TFIIIC110, TFIIIC102, TFIIIC90 and TFIIIC63, and TFIIIC35. GTF3C3/TFIIIC102 appears to be important for stable complex formation and recruitment of RNA polymerase III by interacting with TFIIIB90, TBP, and TFIIIC63. GTF3C3/TFIIIC102 has been shown to also interact with DEDD and FLAME-3 proteins. This interaction may function to translocate GTF3C3/TFIIIC102 to the nucleus and regulate TFIIIC activity.

Gene ID: 9330

NCBI Accession: NP_036218

UniProt: Q9Y5Q9