General Transcription Factor 3C Polypeptide 3 (GTF3C3) (AA 100-150) antibody
This Rabbit Polyclonal antibody specifically detects General Transcription Factor 3C Polypeptide 3 in IP. It exhibits reactivity toward Human.
Catalog No. ABIN7452340
$538.15
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Quick Overview for General Transcription Factor 3C Polypeptide 3 (GTF3C3) (AA 100-150) antibody (ABIN7452340)
Target
General Transcription Factor 3C Polypeptide 3 (GTF3C3)
Reactivity
Human
Host
Rabbit
Clonality
Polyclonal
Conjugate
Un-conjugated
Application
Immunoprecipitation (IP)
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Binding Specificity
- AA 100-150
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Purpose
- Rabbit anti-GTF3C3/TFIIIC102 Antibody, Affinity Purified
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Purification
- Affinity Purified
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Immunogen
- between AA 100 and 150
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Isotype
- IgG
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Application Notes
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IP: 2 - 5 μg/mg lysate
WB: Not recommended. Use rabbit anti-GTF3C3/TFIIIC102 antibody A301-238A.
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Restrictions
- For Research Use only
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Concentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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Expiry Date
- 12 months
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- General Transcription Factor 3C Polypeptide 3 (GTF3C3)
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Alternative Name
- GTF3C3/TFIIIC102
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Background
- Background: General transcription factor 3C polypeptide 3 (GTF3C3/TFIIIC102) is a subunit of the TFIIIC DNA-binding factor required for transcription of tRNA and 5S rRNA genes by RNA polymerase III. Human TFIIIC is composed of six subunits: TFIIIC220, TFIIIC110, TFIIIC102, TFIIIC90 and TFIIIC63, and TFIIIC35. GTF3C3/TFIIIC102 appears to be important for stable complex formation and recruitment of RNA polymerase III by interacting with TFIIIB90, TBP, and TFIIIC63. GTF3C3/TFIIIC102 has been shown to also interact with DEDD and FLAME-3 proteins. This interaction may function to translocate GTF3C3/TFIIIC102 to the nucleus and regulate TFIIIC activity.
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Gene ID
- 9330
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NCBI Accession
- NP_036218
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UniProt
- Q9Y5Q9
Target
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