H2AFX antibody (C-Term)

Catalog No. ABIN7448589

This anti-H2AFX antibody is a Rabbit Polyclonal antibody detecting H2AFX in IHC. Suitable for Human and Mouse.

Quick Overview for H2AFX antibody (C-Term) (ABIN7448589)

Target: H2AFX (H2A Histone Family, Member X (H2AFX))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This H2AFX antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-H2AFX Antibody

Binding Specificity: C-Term

Purpose: Rabbit anti-H2AX IHC Antibody, Affinity Purified

Predicted Reactivity: Bovine,Dog,Rabbit,Guinea pig_10141,Pig,Monkey,Gorilla,Chinese hamster,Little brown bat,Thirteen-lined ground squirrel,Crab-eating macaque

Purification: Affinity Purified

Immunogen: C-terminus

Isotype: IgG

Application Details

Application Notes: 1:100 - 1:500

Restrictions: For Research Use only

Handling

Concentration: 100 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for H2AFX

Target: H2AFX (H2A Histone Family, Member X (H2AFX))

Alternative Name: H2AX

Background: Background: H2AX is a member of the histone H2A family. The four core histones involved in the formation of the nucleosome structure of compacted chromatin are H2A, H2B, H3, and H4. H2AX may function to facilitate DNA repair, and recent studies have shown that H2AX is required for the maintenance of genomic stability.

Gene ID: 3014

NCBI Accession: NP_002096

UniProt: P16104

Pathways: Telomere Maintenance, DNA Damage Repair, Positive Regulation of Response to DNA Damage Stimulus