MCM6 antibody (C-Term)

Catalog No. ABIN7448657

The Rabbit Polyclonal anti-MCM6 antibody is suitable to detect MCM6 in samples from Human and Mouse. It has been validated for IHC.

Quick Overview for MCM6 antibody (C-Term) (ABIN7448657)

Target: MCM6 (Minichromosome Maintenance Complex Component 6 (MCM6))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MCM6 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-MCM6 Antibody

Binding Specificity: C-Term

Purpose: Rabbit anti-MCM6 IHC Antibody, Affinity Purified

Predicted Reactivity: Bovine,Dog,Horse,Guinea pig_10141,Panda,Orangutan,Monkey,Gorilla,Chimpanzee,Crab-eating macaque,Thirteen-lined ground squirrel,Northern white-cheeked gibbon,Small-eared galago

Purification: Affinity Purified

Immunogen: Between AA 775 and C-term

Isotype: IgG

Application Details

Application Notes: 1:100 - 1:500

Restrictions: For Research Use only

Handling

Concentration: 100 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for MCM6

Target: MCM6 (Minichromosome Maintenance Complex Component 6 (MCM6))

Alternative Name: MCM6

Background: Background: The MCM (Mini-Chromosome Maintenance) complex is a key component of the pre-replication complex involved in replication licensing which restricts DNA replication to only once per cell cycle. The MCM complex is a heterohexamer of MCM2, MCM3, MCM4, MCM5, MCM6, and MCM7. MCM6 is part of the core MCM complex that includes MCM4, MCM6, and MCM7. The core complex possesses DNA helicase activity.

Gene ID: 4175

NCBI Accession: NP_005906

UniProt: Q14566

Pathways: DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA