CRTC2 antibody (AA 300-350)

Catalog No. ABIN7448840

The Rabbit Polyclonal anti-CRTC2 antibody is suitable to detect CRTC2 in samples from Human. It has been validated for IHC.

Quick Overview for CRTC2 antibody (AA 300-350) (ABIN7448840)

Target: CRTC2 (CREB Regulated Transcription Coactivator 2 (CRTC2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CRTC2 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-CRTC2 Antibody

Binding Specificity: AA 300-350

Purpose: Rabbit anti-TORC2 IHC Antibody, Affinity Purified

Predicted Reactivity: Mouse,Rat,Dog,Horse,Rabbit,Pig,Panda,Orangutan,Monkey,Gorilla,Chimpanzee,Little brown bat,Small-eared galago,Chinese hamster,Thirteen-lined ground squirrel,White-tufted-ear marmoset

Purification: Affinity Purified

Immunogen: Between AA 300 and 350

Isotype: IgG

Application Details

Application Notes: 1:100 - 1:500

Restrictions: For Research Use only

Handling

Concentration: 250 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for CRTC2

Target: CRTC2 (CREB Regulated Transcription Coactivator 2 (CRTC2))

Alternative Name: TORC2

Background: Background: TORC2 (transducer of regulated CREB activity 2) is part of a family of CREB (cAMP response element-binding protein) coactivators that also includes TORC1 and TORC3. These proteins function to activate CREB-dependent transcription in response to cAMP and calcium signaling pathways. TORC2 has been found to be pivotal to the process of gluconeogenesis.

Gene ID: 200186

NCBI Accession: NP_859066

UniProt: Q53ET0

Pathways: AMPK Signaling, Carbohydrate Homeostasis