CORO1B antibody (AA 450-489)

Catalog No. ABIN7448943

Product Details anti-CORO1B Antibody

Target: CORO1B (Coronin, Actin Binding Protein, 1B (CORO1B))

Binding Specificity: AA 450-489

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CORO1B antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Purpose: Rabbit anti-Coronin 2 IHC Antibody, Affinity Purified

Predicted Reactivity: Mouse,Orangutan,Monkey,Gorilla,Chimpanzee,Thirteen-lined ground squirrel,White-tufted-ear marmoset,Northern white-cheeked gibbon,Crab-eating macaque

Purification: Affinity Purified

Immunogen: Between AA 450 and 489

Isotype: IgG

Application Details

Application Notes:

IHC-IF: 1:50 - 1:500

IHC: 1:100 - 1:500

Restrictions: For Research Use only

Handling

Concentration: 250 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for CORO1B

Target: CORO1B (Coronin, Actin Binding Protein, 1B (CORO1B))

Alternative Name: Coronin 2 (CORO1B Products)

Synonyms: CORO1B antibody, cb1093 antibody, fc02d01 antibody, wu:fc02d01 antibody, zgc:165637 antibody, CORONIN-2 antibody, cor-1 antibody, coroninse antibody, Coronin-1B antibody, coronin 1B antibody, coronin, actin binding protein, 1B antibody, coronin, actin binding protein 1B antibody, CORO1B antibody, coro1b antibody, Coro1b antibody

Background: Background: Coronin 2 is an F-actin binding protein that plays an important role in processes involving actin dynamics such as fibroblast migration, and phagocytosis. Coronin 2 influences actin dynamics by promoting actin depolymerization. It has been shown to interact with the Arp2/3 complex and inhibit Arp2/3-induced actin nucleation. Additionally, it can regulate motility by regulating the actin severing and disassembling activity of cofilin.

Gene ID: 57175

NCBI Accession: NP_065174

UniProt: Q9BR76