SF3B2 antibody (AA 775-825)

Catalog No. ABIN7449024

The Rabbit Polyclonal anti-SF3B2 antibody (ABIN7449024) specifically detects SF3B2 in IHC and IF (p). The antibody is reactive with Human and Mouse samples.

Quick Overview for SF3B2 antibody (AA 775-825) (ABIN7449024)

Target: SF3B2 (Splicing Factor 3b, Subunit 2, 145kDa (SF3B2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SF3B2 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-SF3B2 Antibody

Binding Specificity: AA 775-825

Purpose: Rabbit anti-SF3b145/SAP145 IHC Antibody, Affinity Purified

Predicted Reactivity: Rat,Bovine,Dog,Horse,Rabbit,Pig,Panda,Monkey,Gorilla,Chimpanzee,Tasmanian devil,Ferret,Chinese hamster,African elephant,Northern white-cheeked gibbon,White-tufted-ear marmoset,Small-eared galago,Little brown bat,Gray short-tailed opossum,Thirteen-lined ground squirrel,Naked mole rat,Crab-eating macaque

Purification: Affinity Purified

Immunogen: Between AA 775 and 825

Isotype: IgG

Application Details

Application Notes:

IHC-IF: 1:50 - 1:500

IHC: 1:100 - 1:500

Restrictions: For Research Use only

Handling

Concentration: 250 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for SF3B2

Target: SF3B2 (Splicing Factor 3b, Subunit 2, 145kDa (SF3B2))

Alternative Name: SF3b145/SAP145

Background: Background: SF3b145/SAP145 is a 145 kDa subunit of the splicing factor 3B (SF3B) protein complex. The SF3B complex is composed of at least 8 subunits (SF3B1 through SF3B8). SF3A along with SF3B and a 12S RNA unit are components of the 17S U2 small nuclear ribonucleoprotein complex (U2 snRNP) involved in pre-mRNA splicing. In this complex SF3B2 interacts directly with SF3B4 and associates with the pre-mRNA upstream of the branch site at the anchoring site. SF3A and SF3B may play a role in anchoring the U2 snRNP to the pre-mRNA upstream of the intron's branch site.

Gene ID: 10992

UniProt: Q13435