SF3B2 antibody (AA 616-895)

Catalog No. ABIN7170622

Product Details anti-SF3B2 Antibody

Target: SF3B2 (Splicing Factor 3b, Subunit 2, 145kDa (SF3B2))

Binding Specificity: AA 616-895

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SF3B2 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Splicing factor 3B subunit 2 protein (616-895AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for SF3B2

Target: SF3B2 (Splicing Factor 3b, Subunit 2, 145kDa (SF3B2))

Alternative Name: SF3B2 (SF3B2 Products)

Synonyms: 145kDa antibody, 2610311M13Rik antibody, 2810441F20Rik antibody, B230398H18Rik antibody, SAP145 antibody, SF3b1 antibody, SF3b145 antibody, SF3b150 antibody, SF3B2 antibody, cus1 antibody, sap145 antibody, sf3b145 antibody, sf3b150 antibody, Cus1 antibody, SF3B145 antibody, splicing factor 3b, subunit 2 antibody, splicing factor 3b subunit 2 antibody, splicing factor 3B subunit 2 antibody, splicing factor 3b subunit 2 L homeolog antibody, Sf3b2 antibody, SF3B2 antibody, LOC714747 antibody, sf3b2.L antibody, sf3b2 antibody

Background:

Background: Subunit of the splicing factor SF3B required for \\\'A\\\' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the \\\'E\\\' complex. Belongs also to the minor U12-dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mRNA intron.

Aliases: SF3B2 antibody, SAP145 antibody, Splicing factor 3B subunit 2 antibody, Pre-mRNA-splicing factor SF3b 145 kDa subunit antibody, SF3b145 antibody, Spliceosome-associated protein 145 antibody, SAP 145 antibody

UniProt: Q13435