MERTK antibody (AA 200-250)

Catalog No. ABIN7449268

This Rabbit Polyclonal antibody specifically detects MERTK in WB. It exhibits reactivity toward Human.

Quick Overview for MERTK antibody (AA 200-250) (ABIN7449268)

Target: MERTK (C-Mer Proto-Oncogene Tyrosine Kinase (MERTK))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MERTK antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MERTK Antibody

Binding Specificity: AA 200-250

Purpose: Rabbit anti-MerTK/c-mer Antibody, Affinity Purified

Predicted Reactivity: Panda,Orangutan,Monkey,Chimpanzee

Purification: Affinity Purified

Immunogen: between AA 200 and 250

Isotype: IgG

Application Details

Application Notes: 1:5,000 - 1:20,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for MERTK

Target: MERTK (C-Mer Proto-Oncogene Tyrosine Kinase (MERTK))

Alternative Name: MerTK/c-mer

Background: Background: MerTK/c-mer is one of three members (Tyro3, Axl, and MerTK/c-mer) of the Tyro 3 subfamily of receptor tyrosine kinases (RTK). MerTK/c-mer was cloned from a human B-lymphoblastoid cDNA library. MerTK/c-mer Expression is absent in normal lymphocytes but is found to be ectopically expressed in lymphoblasts and in T-cell ALL cell lines. When activated MerTK/c-mer transmits antiapoptotic and transforming signals and may play a significant role in T-cell leukemogenesis.

Gene ID: 10461

NCBI Accession: NP_006334

UniProt: Q12866

Pathways: RTK Signaling