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Recombinant H2AFX antibody (AA 93-143)

The Rabbit Monoclonal anti-H2AFX antibody has been validated for WB, IHC, ICC and FACS. It is suitable to detect H2AFX in samples from Human.
Catalog No. ABIN7449530
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$547.12
$643.67
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Quick Overview for Recombinant H2AFX antibody (AA 93-143) (ABIN7449530)

Target

See all H2AFX Antibodies
H2AFX (H2A Histone Family, Member X (H2AFX))

Antibody Type

Recombinant Antibody

Reactivity

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Human

Host

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Rabbit

Clonality

  • 121
  • 82
Monoclonal

Conjugate

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This H2AFX antibody is un-conjugated

Application

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Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Clone

BLR059F
  • Binding Specificity

    • 43
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    AA 93-143

    Purpose

    Rabbit anti-H2AX Recombinant Monoclonal Antibody [BLR059F]

    Purification

    Purified

    Immunogen

    between AA 93 and 143 (C-term)

    Isotype

    IgG
  • Application Notes

    IHC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    ICC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.

    WB: 17:40:00

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    100 μg/mL

    Buffer

    Borate Buffered Saline (BBS) pH 8.2 with 0.1 % BSA and 0.09 % Sodium Azide

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    4 °C

    Storage Comment

    2 - 8 °C

    Expiry Date

    12 months
  • Target

    H2AFX (H2A Histone Family, Member X (H2AFX))

    Alternative Name

    H2AX

    Background

    H2AX is a member of the histone H2A family. The four core histones involved in the formation of the nucleosome structure of compacted chromatin are H2A, H2B, H3, and H4. H2AX may function to facilitate DNA repair, and recent studies have shown that H2AX is required for the maintenance of genomic stability. Gamma H2AX is the phosphorylated form of H2AX that results in response to DNA damage.

    Gene ID

    3014

    UniProt

    P16104

    Pathways

    Telomere Maintenance, DNA Damage Repair, Positive Regulation of Response to DNA Damage Stimulus
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