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Recombinant GZMB antibody (AA 19-247)

GZMB Reactivity: Human WB, IHC, ICC, IF (p), mIF Host: Rabbit Monoclonal BLR022E unconjugated Recombinant Antibody

Catalog No. ABIN7449556

Datasheet as PDF

Target See all GZMB Antibodies

GZMB (Granzyme B (GZMB))

Antibody Type

Recombinant Antibody
Binding Specificity
18

16

13

10

10

4

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1
AA 19-247
Reactivity
132

49

24

12

4

4

3

1
Human
Host
85

50

2
Rabbit
Compatible Secondaries
Clonality
83

54
Monoclonal
Conjugate
82

13

7

3

3

3

3

3

3

3

2

1

1

1

1

1

1

1

1

1

1

1

1

1
This GZMB antibody is un-conjugated
Application
72

45

42

41

19

18

17

14

13

10

9

6

6

5

2

2

2

1

1

1

1

1
Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Multiplex Immunofluorescence (mIF)

Purpose

Rabbit anti-Granzyme B Recombinant Monoclonal Antibody [BLR022E]

Immunogen

residues 19-247 (mature protein)

Clone

BLR022E

Isotype

IgG

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anti-Granzyme B (GZMB) (AA 21-247) antibody
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GZMB Reactivity: Human WB, IHC, StM Host: Mouse Monoclonal GZMB-3014 unconjugated

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GZMB Reactivity: Human, Non-Human Primate FACS Host: Mouse Monoclonal CLB-GB11 unconjugated

anti-Granzyme B (GZMB) (AA 21-130) antibody
GZMB Reactivity: Human, Mouse WB, ELISA, FACS, IHC (p), IF (p), IHC (fro), IF (cc) Host: Rabbit Polyclonal unconjugated

anti-Granzyme B (GZMB) antibody
GZMB Reactivity: Human, Mouse, Rat WB, IHC, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated

anti-Granzyme B (GZMB) (AA 175-203), (C-Term) antibody
GZMB Reactivity: Human WB, FACS, IHC (p) Host: Rabbit Polyclonal RB19353 unconjugated

anti-Granzyme B (GZMB) (AA 21-247) antibody
GZMB Reactivity: Human IHC, ELISA Host: Mouse Monoclonal 2G12G7 unconjugated

anti-Granzyme B (GZMB) (AA 1-247) antibody
GZMB Reactivity: Human WB, IP Host: Rabbit Polyclonal unconjugated

anti-Granzyme B (GZMB) (AA 73-187) antibody
GZMB Reactivity: Human IHC, StM Host: Mouse Monoclonal GZMB-3056 unconjugated

anti-Granzyme B (GZMB) (AA 21-247) antibody
GZMB Reactivity: Human WB, IHC, IF, IHC (p) Host: Mouse Monoclonal 4E4 unconjugated

Application Notes

Optimal working dilution should be determined by the investigator.

Restrictions

For Research Use only
Concentration

1000 μg/mL

Buffer

Borate Buffered Saline (BBS) pH 8.2 with 0.09 % Sodium Azide, BSA-Free

Preservative

Sodium azide

Precaution of Use

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage

4 °C

Expiry Date

12 months
Target

GZMB (Granzyme B (GZMB))

Alternative Name

Granzyme B (GZMB Products)

Background

Background: Granzyme B is a member of the granzyme subfamily of proteins, part of the peptidase S1 family of serine proteases. The preproprotein is secreted by natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) and proteolytically processed to generate the active protease, which induces target cell apoptosis. This protein also processes cytokines and degrades extracellular matrix proteins, and these roles are implicated in chronic inflammation and wound healing [taken from NCBI Entrez Gene (Gene ID: 3002)]

Gene ID

3002

NCBI Accession

NP_004122

UniProt

P10144

Pathways

Apoptosis, Caspase Cascade in Apoptosis