Selenoprotein S antibody (AA 125-175)

Catalog No. ABIN7449819

This anti-Selenoprotein S antibody is a Rabbit Polyclonal antibody detecting Selenoprotein S in WB and IP. Suitable for Human.

Quick Overview for Selenoprotein S antibody (AA 125-175) (ABIN7449819)

Target: Selenoprotein S (SELS)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Selenoprotein S antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-Selenoprotein S Antibody

Binding Specificity: AA 125-175

Purpose: Rabbit anti-Selenoprotein S Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: Between AA 125 and 175

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: 1:1,000 - 1:5,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for Selenoprotein S

Target: Selenoprotein S (SELS)

Alternative Name: Selenoprotein S

Background: Background: Selenoprotein S (SELS) is involved in the degradation process of misfolded endoplasmic reticulum (ER) luminal proteins. Selenoprotein S participates in the transfer of misfolded proteins from the ER to the cytosol, where they are destroyed by the proteasome in a ubiquitin-dependent manner. It probably acts by serving as a linker between DERL1, which mediates the retrotranslocation of misfolded proteins into the cytosol, and the ATPase complex VCP, which mediates the translocation and ubiquitination [taken from the Universal Protein Resource (UniProt) Q9BQE4].

Gene ID: 55829

NCBI Accession: NP_982298

UniProt: Q9BQE4

Pathways: Cellular Response to Molecule of Bacterial Origin, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Cell RedoxHomeostasis, Negative Regulation of intrinsic apoptotic Signaling, SARS-CoV-2 Protein Interactome