alpha Adaptin antibody (AA 600-650)

Catalog No. ABIN7449957

The Rabbit Polyclonal anti-alpha Adaptin antibody (ABIN7449957) specifically detects alpha Adaptin in WB and IP. The antibody is reactive with Human samples.

Quick Overview for alpha Adaptin antibody (AA 600-650) (ABIN7449957)

Target: alpha Adaptin (AP2A1) (Adaptor-Related Protein Complex 2, alpha 1 Subunit (AP2A1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This alpha Adaptin antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-alpha Adaptin Antibody

Binding Specificity: AA 600-650

Purpose: Rabbit anti-Alpha-adaptin Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: Between AA 600 and 650

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for alpha Adaptin

Target: alpha Adaptin (AP2A1) (Adaptor-Related Protein Complex 2, alpha 1 Subunit (AP2A1))

Alternative Name: Alpha-adaptin

Background: Background: Alpha-adaptin A is a subunit of the adaptor protein 2 (AP-2) complex found in clathrin coated vesicles. The AP-2 complex is a heterotetramer consisting of two large adaptins (alpha or beta), a medium adaptin (mu), and a small adaptin (sigma). The complex is part of the protein coat on the cytoplasmic face of coated vesicles which links clathrin to receptors in vesicles [taken from NCBI Entrez Gene (Gene ID: 160)].

Gene ID: 160

NCBI Accession: NP_055018

UniProt: O95782

Pathways: Notch Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, EGFR Downregulation