CIR1 antibody (AA 400-450)

Catalog No. ABIN7450122

This anti-CIR1 antibody is a Rabbit Polyclonal antibody detecting CIR1 in WB and IP. Suitable for Human.

Quick Overview for CIR1 antibody (AA 400-450) (ABIN7450122)

Target: CIR1

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CIR1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-CIR1 Antibody

Binding Specificity: AA 400-450

Purpose: Rabbit anti-CIR1 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 400 and 450

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for CIR1

Target: CIR1

Background: Background: Corepressor interacting with RBPJ (CIR1) may modulate splice site selection during alternative splicing of pre-mRNAs (by similarity). CIR1 regulates transcription and acts as a corepressor for RBPJ. Recruits RBPJ to the Sin3-histone deacetylase complex (HDAC) and is required for RBPJ-mediated repression of transcription [taken from the Universal Protein Resource (UniProt) Q86X95].

Gene ID: 9541

NCBI Accession: NP_004873

UniProt: Q86X95