PPFIBP1 antibody (AA 175-225)

Catalog No. ABIN7450418

Product Details anti-PPFIBP1 Antibody

Target: PPFIBP1 (PTPRF Interacting Protein, Binding Protein 1 (Liprin beta 1) (PPFIBP1))

Binding Specificity: AA 175-225

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPFIBP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Purpose: Rabbit anti-Liprin beta 1 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: Between AA 175 and 225

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for PPFIBP1

Target: PPFIBP1 (PTPRF Interacting Protein, Binding Protein 1 (Liprin beta 1) (PPFIBP1))

Alternative Name: Liprin beta 1 (PPFIBP1 Products)

Synonyms: liprin-beta-1 antibody, L2 antibody, SGT2 antibody, hSGT2 antibody, hSgt2p antibody, 4632409B19Rik antibody, AW214454 antibody, AW261454 antibody, PPFIA binding protein 1 antibody, PTPRF interacting protein, binding protein 1 (liprin beta 1) antibody, PTPRF interacting protein, binding protein 1 (liprin beta 1) S homeolog antibody, Ppfibp1 antibody, ppfibp1 antibody, ppfibp1.S antibody, PPFIBP1 antibody

Background: Background: Liprin beta 1 is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. It has been proposed that liprins are multivalent proteins that form complex structures and act as scaffolds for the recruitment and anchoring of LAR family of tyrosine phosphatases. Liprin beta 1 was found to interact with S100A4, a calcium-binding protein related to tumor invasiveness and metastasis. In vitro experiments demonstrated that the interaction inhibited the phosphorylation of this protein by protein kinase C and protein kinase CK2 [taken from NCBI Entrez Gene (Gene ID: 8496)].

Gene ID: 8496

NCBI Accession: NP_803193

UniProt: Q86W92