MAP3K4 antibody (AA 75-125)

Catalog No. ABIN7450441

This Rabbit Polyclonal antibody specifically detects MAP3K4 in WB and IP. It exhibits reactivity toward Human.

Quick Overview for MAP3K4 antibody (AA 75-125) (ABIN7450441)

Target: MAP3K4 (Mitogen-Activated Protein Kinase Kinase Kinase 4 (MAP3K4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAP3K4 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-MAP3K4 Antibody

Binding Specificity: AA 75-125

Purpose: Rabbit anti-MEKK4 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: Between AA 75 and 125

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for MAP3K4

Target: MAP3K4 (Mitogen-Activated Protein Kinase Kinase Kinase 4 (MAP3K4))

Alternative Name: MEKK4

Background: Background: Mitogen-activated protein kinase kinase kinase 4 (MEKK4) is a component of a protein kinase signal transduction cascade. MEKK4 activates the CSBP2, P38 and JNK MAPK pathways, but not the ERK pathway. Specifically phosphorylates and activates MAP2K4 and MAP2K6 [taken from the Universal Protein Resource (UniProt) Q9Y6R4].

Gene ID: 4216

NCBI Accession: NP_005913

UniProt: Q9Y6R4

Pathways: MAPK Signaling