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POLH antibody (AA 690-713)

This Rabbit Polyclonal antibody specifically detects POLH in WB and IP. It exhibits reactivity toward Human.
Catalog No. ABIN7450582
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$457.43
$538.15
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Quick Overview for POLH antibody (AA 690-713) (ABIN7450582)

Target

See all POLH Antibodies
POLH (Polymerase (DNA Directed), eta (POLH))

Reactivity

  • 43
  • 13
  • 12
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Host

  • 43
  • 3
Rabbit

Clonality

  • 45
  • 1
Polyclonal

Conjugate

  • 19
  • 4
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This POLH antibody is un-conjugated

Application

  • 33
  • 13
  • 13
  • 13
  • 8
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
  • 1
Western Blotting (WB), Immunoprecipitation (IP)
  • Binding Specificity

    • 15
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 690-713

    Purpose

    Rabbit anti-PolH Antibody, Affinity Purified

    Predicted Reactivity

    Mouse

    Purification

    Affinity Purified

    Immunogen

    between AA 690 and 713

    Isotype

    IgG
  • Application Notes

    IP: 2 - 10 μg/mg lysate

    WB: 1:2,000 - 1:10,000

    Restrictions

    For Research Use only
  • Concentration

    200 μg/mL

    Buffer

    Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    4 °C

    Expiry Date

    12 months
  • Target

    POLH (Polymerase (DNA Directed), eta (POLH))

    Alternative Name

    PolH

    Background

    Background: PolH is a DNA polymerase specifically involved in DNA repair and somatic hypermutation. Defects in PolH result in a variant type of xeroderma pigmentosum, a disease characterized by sunlight hypersensitivity, increased incidence of cancer, and neurological abnormalities.

    Gene ID

    5429

    NCBI Accession

    NP_006493

    UniProt

    Q9Y253

    Pathways

    DNA Damage Repair
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