SLC46A1 antibody (AA 225-275)

Catalog No. ABIN7450740

Product Details anti-SLC46A1 Antibody

Target: SLC46A1 (Solute Carrier Family 46 (Folate Transporter), Member 1 (SLC46A1))

Binding Specificity: AA 225-275

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC46A1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Purpose: Rabbit anti-SLC46A1 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: Between AA 225 and 275

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for SLC46A1

Target: SLC46A1 (Solute Carrier Family 46 (Folate Transporter), Member 1 (SLC46A1))

Alternative Name: SLC46A1 (SLC46A1 Products)

Synonyms: G21 antibody, HCP1 antibody, PCFT antibody, RGD1309472 antibody, TRPE antibody, 1110002C08Rik antibody, D11Ertd18e antibody, Pcft antibody, solute carrier family 46 member 1 antibody, solute carrier family 46 (folate transporter), member 1 antibody, solute carrier family 46, member 1 antibody, SLC46A1 antibody, slc46a1 antibody, Slc46a1 antibody

Background: Background: Solute carrier family 46 member 1 (SLC46A1) has been shown to act both as an intestinal proton-coupled high-affinity folate transporter and as an intestinal heme transporter which mediates heme uptake from the gut lumen into duodenal epithelial cells. The iron is then released from heme and may be transported into the bloodstream. Dietary heme iron is an important nutritional source of iron. SLC46A1 shows a higher affinity for folate than heme [taken from the Universal Protein Resource (UniProt) Q96NT5].

Gene ID: 113235

NCBI Accession: NP_542400

UniProt: Q96NT5

Pathways: Transition Metal Ion Homeostasis, Dicarboxylic Acid Transport