SPTLC1 antibody (AA 423-473)

Catalog No. ABIN7450768

This Rabbit Polyclonal antibody specifically detects SPTLC1 in WB and IP. It exhibits reactivity toward Human.

Quick Overview for SPTLC1 antibody (AA 423-473) (ABIN7450768)

Target: SPTLC1 (serine Palmitoyltransferase, Long Chain Base Subunit 1 (SPTLC1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SPTLC1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-SPTLC1 Antibody

Binding Specificity: AA 423-473

Purpose: Rabbit anti-SPTLC1 Antibody, Affinity Purified

Predicted Reactivity: Orangutan

Purification: Affinity Purified

Immunogen: between AA 423 and 473

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for SPTLC1

Target: SPTLC1 (serine Palmitoyltransferase, Long Chain Base Subunit 1 (SPTLC1))

Alternative Name: SPTLC1

Background: Background: Serine palmitoyltransferase (SPT), which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It converts L-serine and palmitoyl-CoA to 3-oxosphinganine with pyridoxal 5'-phosphate as a cofactor. SPTLC1 (serine palmitoyltransferase, long chain base subunit 1 is the long chain base subunit 1 of serine palmitoyltransferase. Mutations in SPTLC1 were identified in patients with hereditary sensory neuropathy type 1 [taken from NCBI Entrez Gene (Gene ID: 10558)].

Gene ID: 10558

NCBI Accession: NP_006406

UniProt: O15269