BARD1 antibody (AA 250-300)

Catalog No. ABIN7450976

The Rabbit Polyclonal anti-BARD1 antibody is suitable to detect BARD1 in samples from Human. It has been validated for WB and IP.

Quick Overview for BARD1 antibody (AA 250-300) (ABIN7450976)

Target: BARD1 (BRCA1 Associated RING Domain 1 (BARD1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BARD1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-BARD1 Antibody

Binding Specificity: AA 250-300

Purpose: Rabbit anti-BARD1 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 250 and 300

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: 1:500 - 1:2,500

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for BARD1

Target: BARD1 (BRCA1 Associated RING Domain 1 (BARD1))

Alternative Name: BARD1

Background: Background: BRCA1 associated RING domain 1 (BARD1) together with BRCA1 is an E3 ubiquitin ligase. BARD1/BRCA1 has been shown to ubiquinate RNA polymerase II in response to DNA damage. BARD1/BRCA1 ubiquitin ligase activity has also been shown to be important in the prevention of double stranded breaks and the regulation of centrosome number.

Gene ID: 580

NCBI Accession: NP_000456

UniProt: Q99728

Pathways: DNA Damage Repair